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genisi

05/15/12 12:07 PM

#141955 RE: biomaven0 #141942

Can't say I understand the mode of action of their drug though.

Prof. Cohen from the Weizmann Institute, who developed DiaPep277 believes the peptide activates a subgroup of T-cells which down-regulate the pathogenic T-cells that cause type 1 diabetes. This regulation change the cytokine profile secreted by the pathogenic T-cells: pro-inflammatory cytokines, which are lethal to the insulin-producing beta-cells, are replaced by cytokines that can inhibit inflammatory reactions and this change shuts off the immune attack on beta-cells.