Replies to post #78042 on Avid Bioservices Inc (CDMO)

[cjgaddy]

EntDoc, in case U missed it, as ref'd towards the end of today's PS-Imaging PR, they've added a separate webpage for PS-Imaging:
http://www.peregrineinc.com/technology/ps-imaging.html
...as well as a PS-Imaging DATA page:
http://www.peregrineinc.com/technology/ps-imaging/ps-imaging-data.html

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About 124I-PGN650:
124I-PGN650 is a first-in-class phosphatidylserine (PS)-targeting F(ab')(2) fully human monoclonal antibody fragment joined to the PET imaging radio-isotope iodine-124 (124I) that represents a new approach to imaging cancer. PS is a molecule usually located inside the membrane of healthy cells, but "flips" and becomes exposed on the outside of cells that line tumor blood vessels, creating a specific target for the imaging of multiple solid tumor types. In preclinical studies, 124I-PGN650 accumulates in tumor vasculature and provides exceedingly clear in vivo tumor images.
4-3-12: "…with the recent filing of an Investigational New Drug application with the U.S. FDA. [for a 12-pt. 124I-PGN650 Imaging Trial]"
http://ir.peregrineinc.com/releasedetail.cfm?ReleaseID=661456