Replies to post #127887 on Biotech Values

[biomaven0]

Genetically Modified Mosquitoes to Reduce Disease Threat

I recall reading several years ago about what I thought was a really ingenious idea - instead of releasing sterile male insects, you release insects genetically modified to have only male offspring. Even if the offspring didn't carry the same mutation, the modeling indicated that the effect would be quite dramatic.

Haven't heard anything about the idea since - too bad. If the Gates Foundation was smart this is the sort of project they would fund.

Peter

Edit:
This might be the project:

http://www.rachelmcleod.com/genetic_engineering.htm

[genisi]

9. Novel Diabetes Therapy: SGLT2 Inhibitors [e.g. BMY/AZN’s dapagliflozin]

In addition to the point you posted in #msg-64636960, another indication that dapagliflozin might not have been the cause of the imbalance in bladder and breast cancers is the lack of such adverse events in individuals carrying mutations in the SLC5A2 gene, encoding a defected SGLT2 protein (which cause increased glucose excretion).