Replies to post #46186 on NanoViricides Inc. (NNVC)

[Drano]

Sen. Brownback deserves a national monument for sponsoring this progressive act -- how about Brownback Mountain? LOL !

[incubus-now]

good information on the PR. appears they are the leader in Dengue at this point. 50% recovery on a 100% fatal protocol and 30% with complete recovery. would assume Eva is very excited about the prospects. hopefully, this will lead to further testing in the near future and potential fast track approval of the candidate including monetary considerations. keep walking and chewing gum. hopefully this is where the pace picks up. speed walk?

[FORZANANO]

DrFeelgood

Can you explain these two paragraphs:

Thank you.


In addition, we believe that the dengue virus infection was very well controlled in these treated animals. This is evidenced by the significant decrease in the level of the cytokine TNF-alpha in this nanoviricide-treated group, compared to control groups,” he further added.


In ADE, the very high levels of dengue virus in the body lead to a highly dysregulated immune response. This further leads to high levels of TNF-alpha and other inflammatory cytokines. These inflammatory cytokines subsequently play a role in the vascular leakage that is characteristic of severe dengue. In extreme cases, the vascular leakage can lead to potentially fatal hemorrhagic condition. Achieving control over the dengue virus level is generally expected to lead to control over the cytokine levels as well. Demonstration of control of cytokine levels is considered important in that it is generally believed that the cytokine level control will also lead to a controlled dengue disease that does not proceed to its severe states such as DHF.