I googled Topiramate/topamax side effects and got this. Some are significant some are not. While Qnexa may be the most effective it may not be well tolerated by everyone. Which is why i bought in on Arena as well as locaserin may not be the most effective but its safer, and still helps cardiovascular issues. Hopefully they both get approved and see success.
Off emedtv.com
Common Side Effects of Topamax in Adults
Topamax has been studied thoroughly in clinical trials, in which a group of people taking the drug have side effects documented and compared to another group not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
In these studies, the most common Topamax side effects in adults included:
* Unusual sensations, such as burning or tingling (paresthesias) -- in up to 51 percent of people
* Dizziness -- up to 32 percent
* Fatigue -- up to 30 percent
* Drowsiness -- up to 29 percent
* Mental and physical slowing or delays -- up to 21 percent
* Nervousness -- up to 19 percent
* Upper respiratory infection (such as the common cold) -- up to 18 percent
* Coordination problems -- up to 16 percent
* Weight loss -- up to 16 percent (see Topamax Weight Loss)
* Loss of appetite -- up to 15 percent
* Taste changes -- up to 15 percent
* Confusion -- up to 14 percent
* Difficulty with concentration or attention -- up to 14 percent
* Nausea -- up to 14 percent.
Some other common side effects, occurring in 5 to 13 percent of adults, included:
* Diarrhea
* Memory loss
* Anxiety
* Language or speech problems
* Changes in gait (walking pattern)
* Sinus infection or irritation
* Injury
* Insomnia
* Mood problems
* Decreased sense of touch
* Viral infections
* Abdominal pain (stomach pain)
* Joint pain
* Weakness
* Sore throat
* Dry mouth
* Indigestion
* Mood problems
* Back pain.
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