Replies to post #93975 on Biotech Values

[genisi]

No, the correct flow chart is: if the 1st degree has a defined mutation then I will look for that specific mutation in the tested subject (man or woman), no need to look for CNV in case like that. However, when the family history strongly suggests that the breast cancer runs in the family and no mutation has been found in BRCA1/2 then I will look for CNV.