The only issue I have found is that I was running the beta version of IE8 before the full release came out. Now when I try to download IE8 it won't allow it. It get's all the way through the setup process and then when I am prompted to do a restart the error messages start coming about IE8 was not able to be installed on my system.
I tried removing the beta version and I got all kinds of warning messages saying certain programs might not run properly if I continue. So for now I just left things alone.