Replies to post #71111 on Biotech Values

[rkrw]

I guess the 100% move is justified!

[mcbio]

Re: ANDS results in genotype 1a vs. 1b HCV patients

What is the difference between genotype 1a and 1b HCV patients as far as market size? If the bulk of patients are 1a, I might be concerned as the drug was clearly more potent in the 1b type, although it was clearly active in 1a.

[genisi]

ANA598 - data at 4 weeks for the first dose cohort, 200 mg bid, in an ongoing Phase II study:

http://www.anadyspharma.com/pr_pdfs/ana598%204-week%20interim%20results%20final%2012.17.09.pdf

Still a difference between genotypes 1a and 1b but what looks strange here is that VL change was quite similar in genotype 1b and placebo 3.7 and 3.9 (log10 IU/ml) respectively.