Bruker Biospin has been awarded US Patent 7,402,437, “Method and device for analyzing the intracellular chemical state of living cells by nuclear magnetic resonance.”
The inventors listed on the patent are Benjamin Gonzalez, Martial Piotto, and J. Gaspard Huber.
As described in its abstract, the patent describes a method for analyzing the intracellular chemical state of living cells by nuclear magnetic resonance. The method comprises preparing the cell sample and performing an NMR analysis on the sample.
Both steps are carried out at a very low temperature to freeze the biochemical state of the living cells, in order to obtain specific and accurate reproducible measurements of cellular functioning.
The invention also describes the device coupled to the NMR spectrometer for implementing the analysis.
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