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05/08/24 6:20 PM

#689823 RE: learningcurve2020 #689803

When you look at the section of the just-released Nature article entitled:

Generation of autologous dendritic cell vaccines



it describes how the DCs used in this UCLA trial were established:

Monocyte-derived DCs were established from adherent peripheral blood mononuclear cells (PBMC) obtained via leukapheresis performed at the UCLA Hemapheresis Unit, as we have published previously3,6,52.


When you click on the link in the article for the No. 6. footnote I've bolded and colored above, Liau's JAMA article comes up.

6. Liau, L. M. et al. Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial. JAMA Oncol. 9, 112–121 (2023).



I think that suggests that the two methods used (in this trial described in Nature, and in the DCVax-L 3 P3 trial) are the same?

newman2021

05/08/24 11:09 PM

#689871 RE: learningcurve2020 #689803

omg, what an ass. Ok, so you agree that there is a ATL-DC vaccine out there and it helps GBM patients. You and exwannabe both are like none other than AF who claimed on 5/10/22 the trial failed because placebo did better in the progression free survival and the treatment arm pfs failed. And you two are saying ATL-DC is not DcVaxL. Thus, all you three are intentionally lying which is criminal intent; and you all 3 could be just 2 or simply just one.

SkyLimit2022

05/08/24 11:53 PM

#689885 RE: learningcurve2020 #689803

LC,

Scroll down to the end of the Nature Communications publication to see the Ethics Declarations section:


https://www.nature.com/articles/s41467-024-48073-y
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