Replies to post #688217 on NorthWest Biotherapeutics Inc (NWBO)

[georgebailey]

Hyperopia here is a path to 1000 per month
Phase 1A Sawston 50/mo
Phase 1B Sawston 50/mo
100 x Eden’s efficiencies @12 is 1000 with room for downtime maintenance.

[Chiugray]

Hyperopia, Here's a possible scenario I came up with for Sawston to handle at least 12K to 15K patients per year. Your thoughts on if this is in the ballpark would be appreciated.

Model of Sawston Mfg Facility
% of totalSq Ft
- Cleanroom/mfg suite 35% 30,921
- QC, Release Testing 15% 13,252
- Cryo cold storage 10% 8,835
- Other, R&D labs 15% 13,252
- Offices, warehouse, etc 25% 22,086
- Total Sawston facility 100% 88,345

- # of Mfg Suites: 28 (28 X 2,200 sq ft = 30,800 sq ft, at 100% capacity)
- Sq ft per mfg suite: 2,200 (2 suites "occupying approximately 4,400 square feet on the ground floor")
- # of Eden systems per suite: 1 (Automolous datapoint: typical cleanroom 100 meter sq (1,100 sq ft) fits 30 digitized workstations)
- # of cartridges per Eden system: 12 (NWBO 2/6/24 press release: "multiple patients (potentially up to a dozen or so)")
- 8 days mfg process, # turns/mo: 3.75 ("manufacturing process today… about eight days for - DCVax-L", 30 days divided by 8 hrs/day)
- Total patients per month: 1,260
- Equals capacity for 15,120 patients per year