The only immediate threat to AVXL is Missling. His track record of fumbles, stumbles, goal post moving, cherry picking of data, missed timelines, and horrible communications (like today’s latest way-too-long, way-too-dense, and boring presentation) has destroyed whatever credibility Anavex/Missling may have had at the start of this journey. None of this is opinion. It’s well documented with a simple Google search.