Replies to post #251395 on Biotech Values

[dewophile]

Link to the NEJM publication

https://www.nejm.org/doi/full/10.1056/NEJMoa2312323

Small trial, but the slight improvement in the tx arm vs decline in the control arm translated to a p-value of.007.
a small molecule glp-1 would probably get through the BBB more efficiently and have better efficacy (or similar efficacy w better tolerability bc can dose it lower systemically)