Replies to post #682055 on NorthWest Biotherapeutics Inc (NWBO)

[skitahoe]

This is a pay me now or pay me later situation, if the longs are right. Now, before UK approval you can pay in the $.50 cent range, after UK approval it's possible the decimal point could move a place to the right if the media coverage of this new paradigm in cancer treatment receives the right sort of publicity. If the shorts are right, hard to say if the company survives to do more trials.

Note the early phase trials at UCLA, recognize that with Poly-ICLC and/or Keytruda they're achieving 50% survival at 5 years or beyond, but only when they're combined with DCVax-L. If additional trials were ever needed this would totally blow away anything happening in GBM, the regulators can read all about it from the Phase 1, IMHO it would be malpractice not to treat a patient with this off label, but if the regulators want to be deaf, dumb and blind they can ignore it and demand additional trials before an approval.

Gary

[Horseb4CarT]

If you look at what posts have been stickied here you can get a good overview of nwbo and dcvax.

For further reading you can look at X posts by bio99 and Baxe. Baxe did a stupendous treatise all about nwbo and dcvax that would be a great overview by itself.

Then you can find and read presentations such as the one presented May 10, 2022 at the NYAS (NY Academy of Science) and Dr Marnix Bosch presentations regarding Method of Action of dcvax and other ASCO presentations, and much, much more!

Jumping ahead to current events, Nwbo submitted a Marketing Approval Application to the MHRA in the UK for approval of dcvax-l for new and recurrent glioblastoma multiforme and the approval decision could come from any day now to less than 3 months.

A case was just made by a poster that given MHRA newsletter noted applications for 150 day consideration submitted late last year would be “upgraded” for a now shorter approval process, the approval decision could potentially be made within the next 10 days. The MAA for DCVax-L was submitted December 20-21, 2023 and would therefore fit the bill.

The endless FUD postings are relentless and getting worse as progress has been made, and nwbo has initiated a law suit against more than a handful of Wall Street market makers for allegedly spoofing (manipulating) the nwbo share transactions, however the shenanigans continue imo.

This is a good time and price to initiate a position in nwbo imo but that’s not advice and please do your own due diligence before committing money on any stock or not. I am one of the looonnnggg time holders and accumulator of the nwbo shares and for myself I believe the current risk reward ratio is compelling given the still low share price and waiting for approval or not of the MAA after a successful phase 3 trial and a peer reviewed paper on the same published in one of the premier medical journals.

What I just posted is a start for you however please do the noted reading for better due diligence and regardless, don’t get in over your head like risking money you can’t afford to lose in any pre commercial pre earnings stock imo.

[mike00h]

For any new NWBO investor, do not miss the following items to help you understand background on this company.

1. A fellow named Tom Baxendale put together this history and summary. It’s from last May so it could use an update, but it's a great resource:
https://drive.google.com/file/d/1zr8aHIN5ZZLO9wBf4HlJTc-C-mfajb0w/view

2. The Journal of the American Medical Association published this peer reviewed article on the phase 3 trial results, on November, 2022:
https://jamanetwork.com/journals/jamaoncology/fullarticle/2798847?resultClick=1

3. NWBO alleges market manipulation, filed a civil lawsuit. Top Wall Street law firm takes the case on contingency. Progress here:
https://www.courtlistener.com/docket/66579590/northwest-biotherapeutics-inc-v-canaccord-genuity-llc/

4. This is some recent commentary:
https://www.reddit.com/r/wallstreetbets/comments/1995j9e/the_american_system_profits_over_life_a_tiny/?sort=new

5. Some credible doctors talking about their results and experience:

6. NWBO filed for regulatory approval from MHRA (Great Britain) on December 20, 2023. More than 90 days have passed and it does not appear an RFI (pause) was issued. MAA’s stated 150 calendar day goal means approval on or before May 19. They announce here, twice a month.
https://www.gov.uk/government/publications/marketing-authorisations-granted-in-2024

BE SCEPTICAL! A huge amount of fear, uncertainty, doubt (FUD) and outright lies are posted on this board.