Replies to post #681262 on NorthWest Biotherapeutics Inc (NWBO)

[flipper44]

No, DCVax-l was intentionally constructed to
work within the natural framework of the immune system, and as used in the DCVax-l trial, it stops progression and kills the remaining tumor cells. That’s why stabilization signifies response. DCVax-l targets hundreds of antigens to reduce the likelihood of tumor escape.

Car-T, even when used with chemo, aggressively ‘blows apart’ tumors which spread nonresponding cancer cells throughout the body, and because it only targets one or two antigens, easily allows the cancer cells to escape. That’s why partial or complete tumor response (transient) deceives the patient and apparently the researchers.

[iclight]

I could target hitting a car with a pillow 10 times and be successful 10 times but it does nothing to the car. Just like DCVax.