Yeah I don’t see it getting approved. Listening now. The one Dr did bring up the non ring sideroblasts that I mentioned as a potential benefit group with further study but the study didn’t clearly give granularity on specifics I would want to see to give something as important as FDA approval. There is maybe potential with further study especially that subgroup, but not with the current data I see in my opinion and I don’t think that subgroup had real big responses (just better than current standard by a bit). Maybe another Dr will give some sort of angle that everyone missed but as of now I don’t see it getting approved.
Edit- ah it looked like there were a couple super responders I think given what current speaker showed. That explains the bit of outlier numbers on the responders vs the whole arm receiving Imetelstat. Too bad there weren’t more, those patients should be closely followed and looked into more.
PS- I’m not a fan of subjective questions to determine fatigue over, say, O2 stats or physically measurable numbers…
All in my opinion only.