Replies to post #451414 on Anavex Life Sciences Corp (AVXL)

[Rubyred77]

Why would patients that completed the trial enroll in another trial and risk being in the placebo group when they are already on the therapy for how many years?

They would need an entirely new set of patients.

[Joseph_K]

EXCELLENCE trial dates:
Actual Study Start Date : July 1, 2020
Actual Primary Completion Date : June 1, 2023
Actual Study Completion Date : June 30, 2023
https://classic.clinicaltrials.gov/ct2/show/NCT04304482

12 week treatment of each patient, if that's what you wanted.

I'll add to RubyRed's excellent point, that the trial would be disqualified on the ground that the subjects, having been on blarcamesine previously, are not appropriate since the prior treatment might be affecting the things being measured.

[Steady_T]

Recruiting will take the longest amount of time. I would expect the trial size to be larger and probably a bit longer. Both of those changes would mitigate against a strong placebo effect.

[Investor2014]

Can’t keep the same patients for a new trial.