That's just FDA's poorly written fluff about BDD purpose. There's is no way anyone can make definitive relative safety judgements vs. other treatments without human trials, and Radiogel just ain't there yet. Poor writing abounds, even at FDA.
As far as genotoxicity testing, RDGL already committed to do that. BDD can't change that. The shame is on MK for not communicating the timetable in prior updates.