Replies to post #2582 on Jaguar Health Inc (JAGX)

[oldstocks]

Mytesi / Crofelmer

125MG Tablet Delayed Releases, 30 Tablet Delayed Release of the Brand
$1,300.00

Mytesi (crofelemer) is a member of the antidiarrheals drug class and is commonly used for Diarrhea. The cost for Mytesi oral delayed release tablet 125 mg is around $2,622 for a supply of 60 tablets, depending on the pharmacy you visit.

Each year, more than 1 million cancer patients in the United States receive chemotherapy or radiation. Many patients are treated in outpatient oncology clinics.

A good question to figure out is how much money could JAGX Jaguar and Napo company have in revenues from crofelemer if the OnTarget Study has good results?

If approved and the cost was as above, If half of the 1 million got a 30 day supply of crofelemer, 500,000 a year that would be $650,000,000 now that is just a guess but how many 30 day supplies will people need and how many quit taking it is unknown.
That would be for just the USA alone.
World wide could be $3 Billion
How much of that $ would go to the company??

This could be a huge if everything turns out as we are hoping. But we have to wait for the OnTarget results of the study.

Globally, 57.7% of new cancer cases (9.8 million out of 17 million) required chemotherapy in 2018.

Nearly 25% of cancer patients receive chemotherapy during a given year. Compared to forgoing treatment

Any drug used to treat cancer (including tyrosine kinase inhibitors or TKIs) can be considered chemo, but here chemo is used to mean treatment with conventional cytotoxic (cell-killing) drugs that mainly kill cells that are growing and dividing rapidly. Chemo was once one of the main treatments for CML.

Diarrhea is a common side effect of targeted therapies and new treatments are needed. Up to 95% of patients on tyrosine kinase inhibitors (TKIs) suffer from diarrhea, depending on the TKI used.
The OnTarget study is testing whether the company's plant-based prescription drug crofelemer can prevent or substantially reduce diarrhea and other symptoms of CIOB when any one of the selected 24 different targeted therapies that are associated with diarrhea in patients is initiated.

This would all depend on good results…..
If the results are not good then there is still the use of Crofelemer for AIDS patients and dogs.