Jaguar Health Inc (JAGX)

[oldstocks]

Only FDA conditionally approved product to treat chemotherapy-induced diarrhea (CID) in dogs

https://www.canalevia.com/

PROVIDING COMFORT AND EASING THE BURDEN OF CHEMOTHERAPY-INDUCED DIARRHEA (CID)
IN DOGS

Crofelemer is an inhibitor of two chloride ion (Cl ) channels at the luminal membrane of enterocytes. These channels are responsible for the regulation of Cl influx into the lumen. Crofelemer inhibits the hypersecretion of Cl in chemotherapy-induced diarrhea and normalizes the fluid influx into the GI tract.

https://www.dvm360.com/view/novel-plant-based-drug-now-available-for-the-treatment-of-chemotherapy-induced-diarrhea-in-dogs

Crofelemers are approved by the US FDA for the symptomatic relief of noninfectious diarrhea in adult HIV/AIDS patients on antiretroviral therapy. Crofelemers have demonstrated safety and efficacy in people living with HIV/AIDS in numerous clinical studies when compared with placebo in reducing the frequency of loose/watery bowel movements as well as improvement in stool consistency

https://www.researchgate.net/figure/Summary-of-clinical-trials-investigating-the-use-of-crofelemer-for-secretory-diarrhea_tbl2_252325429


Top Line Data for
Jaguar Health's Pivotal Phase 3 OnTarget Trial for Prophylaxis of Diarrhea in Adult Cancer Patients
Receiving Targeted Therapy Forthcoming


https://www.stocktitan.net/news/JAGX/fda-approves-renewal-of-canalevia-ca1-jaguar-health-s-drug-for-9ykf9wyx1sx0.html

Jaguar Health’s big play for revitalization

https://www.pharmavoice.com/news/rainforest-pharma-jaguar-health-lisa-conte/696735/