Life sciences as a cutthroat business. When I was a kid, my parents had a small medical devices company. My dad focused on making heart and lung machines and my mom focused on making disposable, sterile tubing packs for various surgeries (for example, in an open heart operation you need to connect the patients to multiple machines - heart and lung, blood oxygenator, etc. - and you just want to be able to rip open a package and smoothly connect everything perfectly.)
The company made great products - the best heart and lung machine and high quality tubing packs. But the competition was fierce. The things huge companies would do to cut the legs out from under my parents' company were extensive and underhanded - from sabotage to bribery. If I had not lived through the dirty tricks while they happened, I would not have believed that American companies could act so unethically and ruthlessly. If anyone ever extols the virtues of capitalism to me then I always wonder whether they mean the ideal level playing field where everyone plays by the rules and the best man wins, or whether their version of capitalism encompasses the dirty tricks and use of money to tilt the playing field that is pretty standard.
You can bet that all the powers-that-be will do what they can to foil Anavex. Two things are going for Anavex right now: 1) no one is really making much money from AD or Rett right now so the wall isn't too high and the incentive to crush Anavex is not massive yet, and 2) filing with EMA and other agencies makes it much harder to screw with Anavex in the USA.