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boi568

12/13/23 11:40 AM

#442494 RE: Investor2014 #442491

Anavex used the term Proof of Concept for its successful Phase 2 PDD trial, which was clearly exploratory and not intended to be potentially pivotal. This is in contrast to its successful AD 2b/3 trial, which has already persuaded the EMA to green light a pre submission process, and the 2b/3 AVATAR and upcoming EXCELLENCE trials, which will form the basis for an NDA effort. None of those others were labeled Proof of Concept.

Why did the PDD trial description trigger you? As an investor in Anavex, were you upset by its promising results?
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rayovac812

12/13/23 7:25 PM

#442568 RE: Investor2014 #442491

Too much emotion and too little experienced cool calm review of fact is not a good strategy in biotech investing.



Talking can be agreeable or disagreeable. Being agreeable/disagreeable invokes emotion. AVXL listed the accepted/unaccepted facts. Cool calm reviews are relative in/on adversarial/amiable terms. It gets clear when asking if this will ever be an $8 stock again. Everything else gets filtered and framed by adversarial and oft repeated rhetoric.