Replies to post #649407 on NorthWest Biotherapeutics Inc (NWBO)

[martyDg]

Everyone knows that NATURE pre-print probably won't have an impact when it publicized just like the JAMA.

[exwannabe]

Yes, another paper that asserts the UCLA ATL-DC is very different from DCVax-L. And you wonder why NWBO has never says a peep about these trials being DCVax-L.

One day before each vaccination, DC were pulsed (cocultured) with 100 µg of tumor lysate overnight, washed, and the final product was tested for sterility by Gram stain, mycoplasma, and endotoxin testing prior to injection.

So ATL-DC is made fresh just before use. DCVax-L is used after being frozen. Almost certainly the same differences we see between the 2 in other published sources.

There are plenty of DC vaccines being trials. ATL-DCs have been trialed for 3 decades. NWBO says theirs is better because of some minor tweeks.Yet the ATL-DC used in this trial was clearly different from -L.

Maybe somebody can ask LP at the ASM if ATL-DC is NWBO's property. I doubt it.