Replies to post #649398 on NorthWest Biotherapeutics Inc (NWBO)

[eagle8]

Hankmanhub,

Credit to biosectinvestor:

CSF-1R Inhibition (CSF-1Ri): CSF-1R is a receptor on myeloid cells. By inhibiting this receptor with drugs like PLX3397, you can reduce the number and/or function of immunosuppressive myeloid cells, including TIMs. In the context of GBM, CSF-1Ri aims to reprogram or inhibit these immunosuppressive cells, thereby improving the efficacy of other immunotherapies, and in our case, specifically to improve the efficacy of DCVax-L.

imo CSF1-R doses the right amount of T cells that enter the tumor.

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