Replies to post #417578 on Amarin Corp Plc (AMRN)

[caddiedad]

Thanks LBL for this repost.
“These areas of investigation include cancer, inflammatory bowel disease, infections, Alzheimer’s disease, dementia, and depression. The next decade promises to deepen our understanding of the beneficial effects that EPA may offer beyond cardiovascular risk reduction.”

This agent is readily available for use and has a good safety profile, making it a favourable agent to consider for AD prevention. Currently, Carlsson et al. are conducting a small randomized clinical trial to determine if EPA beneficially affects cerebrovascular function or cognitive performance in cognitively healthy adults at increased risk for AD called Brain Amyloid and Vascular Effects of Eicosapentaenoic Acid (BRAVE-EPA)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537800/

[Pharmacydude]

LBL
Did you notice one of the co-authors is none other than Dr Cynthia Carlsson- aka BRAVE primary investigator (although in that paper she goes by Cindy Carlsson).
The section on BRAVE would have been written by her.
Interesting little piece of trivia



Beyond cardiovascular medicine: potential future uses of icosapent ethyl

Deepak L Bhatt,s1 Mark A Hull,s2 Mingyang Song,s3,s4,s5 Carol Van Hulle,s6 Cindy Carlsson,s7,s8,s9,s10 M John Chapman,s11,s12 and Peter P Toths13,s14

[couldbebetter]

I hope the new formulation of Vascepa (the one management seems
its trying to keep secret) is the one where the drug is absorbed through
the lymphatic system (for better absorption in the lungs & brain...I
think.) If this is the case then perhaps Denner will use it to entice
BP into acquiring Amarin to use this new formulation as an adjunct
drug for the treatment of cancer, especially lung cancer, and Alzheimer's
disease. The key to whether or not the idea is viable may have more
to do with achieving strong enough patent protection more than proving
that the drug works. If Denner could pull that off he will be a real biotech
hero on many levels. I certainly hope Denner is working with Bhatt to
bring whatever plan he has to fruition...Soon!