Since $AVXL's financing agreement with LPC is a "PUT" agreement and not best efforts, Anavex behaves more like a private company owned by Dr.M than a public one. As to why? well only the CEO and BOD know why.
I think we should consider the possibility that a small group of experts at Anavex are dealing with an overwhelming set of data-based possibilities. A huge amount of data and relatively few wrangling it is a formula for predictable delay.