I’m not one for promoting LC’s posts as some do, which I think is silly.
But yes, as I have said for some time, the RWE initiative at FDA and elsewhere will make expanding the label potentially much, much easier and in fact it would not require trials, in that context though trials may still be useful for convincing the medical establishment to utilize DCVax-L for a variety of cancers.
My conjecture is that the new trials with DCVax-L will be RWE driven. Has Merck or Amgen been trying to lay RWE platform to new trials? It could be related to DCVax-L.