Surveys/Polls get different answers based upon how questions are asked so I take them all with a grain of salt. However, I agree in general with several of the points being made. Specifically:
People don't like needles and self injections
Cost is an issue and for weight loss and will be a deterrent to usage. $300 a month seems like a tolerable copay IMO. This is opinion based upon what I've learned/read about what is happening at medspa's/what people have historically paid for Weight loss programs.
It doesn't sound like tolerability/side effects were mentioned. I agree with you that an important aspect of the new "G" (GLP-1, GIP, or Glucagen) I believe tolerability is even more important than whether it is Oral or Sub-q and will eventually determine the degree of market success.
Obesity in and of itself is a big health problem and I don't think the cardio problems of the new "G's" compare to older drugs which created real cardio issues. In fact I think the new G's will be proven to improve overall cardiovascular health. The thyroid cancer risk is de minimis and not seeming to appear in any of the people currently on these drugs.
Last comment is even if the survey were spot on, if only 23% of the obese + overweight people went on a "G" based therapy permanently, we would still be taking about 10's of millions of people in the US alone.
I know several people that started Mounjaro and one Wegovia.
Two of those who started Mounjaro dropped it. One for stomach pain which she says has continued despite being off for three weeks. She is still losing weight. The other was vomiting and dry heaving to the point he did not want to continue.
The guy on Wegovia complains of loss of energy after the shot for a couple of days but is staying the course.
I started Mounjaro over three weeks ago and it is tolerable. Weight loss is consistent with my expectations and plan. I have posted details on X if anyone is interested. The one unexpected side effect is sleep disturbance that seems to run several days after each shot. One favorable effect is that eating satiation is lasting far longer than the 7 days. Guessing it will last two weeks between shots. I'm acting as guinea pig with weight loss as the target, NOT A1C.
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