ae kusterer,
The potential for this base treatment use of DCs was mentioned as the potential answer for ~80% of all diseases with applications eventually reaching into at least high end veterinary care years ago on this board. What we see iwasadiver responding to is the very public validation of an easy assumption from the early science behind the treatment.
The treasure trove of validated antigen targets that are commonly known targets in other cancers makes this research nearly a slam dunk for tissue agnostic designation precisely because this tech UNCOVERS ALL THE HIDDEN PERPS whether in brain cancer, liver cancer, lung cancer or any other solid tumor cancer in its present form. It doesn’t just target a few antigens it goes after them all and with a little help from some friends like Poly ICLC, CSF-1R or checkpoint inhibitors or combined with Direct in residual tumor or treated with Direct first in many cases, some of us are pretty sure what happens and have been for quite some time. C is for “cure” but be careful.. that’s a naughty four letter word in some circles ; ). Best wishes.