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DoTheRightThing

06/27/23 10:17 AM

#420167 RE: Doc328 #420159

That last paragraph really sums it up. Missling knows AD isn't getting approved and is praying for Rett approval to soften the blow to shareholders. If Rett misses which is then followed by AD having to do another 3-5 year trial, this stock is done.

frrol

06/27/23 10:19 AM

#420169 RE: Doc328 #420159

Considering the approval of trofinetide, I'm optimistic on our near-term Rett prospects.

Your observation about Missling always taking the best case scenario is accurate, but that is pretty typical for young biotechs. Of course, it does mislead some, which is unfortunate. But those folks have bigger problems.

sab63090

06/27/23 12:23 PM

#420227 RE: Doc328 #420159

Doc328:

"If Missling feels that AD has the goods to submit an AA, then he should go ahead and do so"

Yes, your quote does give emphasis to what Missling has probably decided NOT to do...sadly I have to admit that I will probably have to accept that after the Excellence Trial result...the bigger potential will (AD) come too many years down the road.....I have to think that's about all I can envision!

Steady_T

06/27/23 12:25 PM

#420232 RE: Doc328 #420159

Thanks for the reply and the analysis.

WolfofMia

06/27/23 5:05 PM

#420296 RE: Doc328 #420159

Good to know you are still invested on AVXL Doc!! Lol

abew4me

06/28/23 10:42 AM

#420433 RE: Doc328 #420159

In light of today's PR, would you like to change your statement?

Quote: "Rett has a 20-25% chance of showing data later this year good enough for an NDA submission in early 2024 (potential decision Q3)."