Replies to post #1215 on Ardelyx Inc (ARDX)

[Cosa]

Not sure, not a doctor or scientist. But Ibsrela is the same drug. Xphozah would probably have the same recommendations to stop usage. Everyone reacts to drugs differently and it may not be best for everyone. But at least approval will give patients another option to try.

Diarrhea was the most common adverse reaction in two randomized, double-blind, placebo-controlled trials of IBS-C. Severe diarrhea was reported in 2.5% of IBSRELA-treated patients. If severe diarrhea occurs, suspend dosing and rehydrate patient.
MOST COMMON ADVERSE REACTIONS
The most common adverse reactions in IBSRELA-treated patients (incidence ≥2% and greater than placebo) were: diarrhea (16% vs 4% placebo), abdominal distension (3% vs <1%), flatulence (3% vs 1%) and dizziness (2% vs <1%).
INDICATION
IBSRELA (tenapanor) is indicated for the treatment of Irritable Bowel Syndrome with Constipation (IBS-C) in adults.