Replies to post #406010 on Amarin Corp Plc (AMRN)

[Monk44]

Denner knows the power of C22H34O2
That's why he's doing what he's doing.

[ziploc_1]

Slevin...Thanks for posting...QUOTE..."Heightened extravasation of the lipoprotein-Aß in T2DM amplifies NEUROVASCULAR INFLAMMATION and neurodegeneration, resulting in accelerated neuronal cell death and premature cognitive decline."

This is another clue as to why the anti-inflammatory effect(as well the lipid lowering effect, of Vascepa) may play a role in palliating Alzheimers(especially when used with statins)...We await the results of the Brave study to soon shed more light on this all too common disease.

This is yet another reason, in addition to reduction of CVD, for type 2 diabetics to be on statins and Vascepa.

[dukesking]

Sleven, Interesting article. Hopefully BRAVE study shows positive outcomes for Vascepa based on the triglyceride rich lipoprotein theory. However, it was disappointing to see PCSK9 and Vupanorsan mentioned as potential therapies but no mention of IPE. Interestingly, Vupanorsan was discontinued by IONIS and Pfizer after disappointing trial results for CVD.
https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-ionis-announce-discontinuation-vupanorsen