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catdaddy

02/20/23 3:28 PM

#404068 RE: scorman1 #404067

And some wonder why their posts are totally discounted.

nidan7500

02/20/23 3:42 PM

#404069 RE: scorman1 #404067

scorman1

[ RETT after Excellence Trial providing revenues]
revenues isn't profits or cash flow.. Rett will generate nothing from such a small patient base...probably cost more to produce than returns
Extremely rare
Fewer than 1,000 US cases per year
such is "orphan status"



IMO, this will become part of the RWD-RWE -ANAVEX ORPHAN DRUG TREAMENT WW TSUNAMI Process/Program.

Steady_T

02/20/23 4:14 PM

#404077 RE: scorman1 #404067

The drug prices for the rare diseases can be $200K + a year according to MIssling.

So Rett may be able to generate a significant chunk of revenue. Once AD is approved I would expect the drug price to drop massively.

Mikesc

02/20/23 4:56 PM

#404090 RE: scorman1 #404067

It is estimated that one in 10,000 girls is born with Rett syndrome. This means about 15,000 girls and women in the US and 350,000 worldwide have the disorder.

sab63090

02/20/23 5:24 PM

#404095 RE: scorman1 #404067

Scorman1

I remember something that Missling said, but forgot where I heard it....didn't he say that the approval for RETT (adult and children) was worth about $6 Bil???

Also, isn't there a voucher for $100 mil...that is out there, but needs to see the Excellence Trial result in order to keep it....

Maybe someone else here can take this on?

rx7171

02/20/23 11:26 PM

#404146 RE: scorman1 #404067

TGD has commented that he expects the Rett to price in the $400-600K per patient.
The total US Rett population is about 10,000.
Do the math.