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rosemountbomber

02/18/23 2:10 PM

#403588 RE: rosemountbomber #403587

And the BS that V did not reduce all cause mortality:

“all-cause mortality (9.8% to 7.2%; HR, 0.70 [95% CI, 0.55–0.90]; P=0.004); for all-cause mortality in the US versus non-US patients, Pinteraction=0.02. Safety and tolerability findings were consistent with the full study cohort.

Conclusions:
Whereas the non-US subgroup showed significant reductions in the primary and key secondary end points, the US subgroup demonstrated particularly robust risk reductions across a variety of individual and composite end points, including all-cause mortality.”

US Reduce-It showed greater benefit in all cause mortality than ROW but even in ROW there still was a benefit although not stat sig as it was 0.09.

https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.119.044440#