Flipper, maybe full disclosure of the OS results of the methylated and unmethylated crossover patients will strongly suggest that GBM patients receiving DCVax-L before progression, should not receive any temodar. I strongly suspect that temodar will be found to be counterproductive for unmethylated GBM patients who post surgery are treated with DCVax-L and I suspect the same will be true for DCVax-L treated methylated GBM patients.