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lefty49

12/06/22 8:03 AM

#544439 RE: DocLee #544434

Doc, its the timing of the PD1. Before or after DCVax. Not a placebo.

"Extra treatment given after primary therapy is referred to as adjuvant (meaning “helper”) therapy, whereas extra treatment given before primary therapy is referred to as neoadjuvant therapy"

flipper44

12/06/22 8:05 AM

#544442 RE: DocLee #544434

Neoadjuvant “Neoadjuvant” therapy is the administration of therapeutic agents before a main treatment. In the case you refer to, this would mean Keytruda prior to recurrent surgery, then both therapies (DCVax + Keytruda) concurrently. However, what actually worked better was Keytruda + DCVax starting after recurrent surgery.