The keytruda side effects and potential toxicity was why I didn’t push my mom to try keytruda, opting instead to stop treatments and try to get some months of no treatments/ctscans/side effects before all the metastases would take their toll.
I’ll probably second guess that decision for a long, long time, but the risks of either sudden death, blood counts and infections, pneumonia, etc without hope of significant life extension seemed like a significant risk of shortening and/or degrading the time left.
Had there been more hope that some percentage of people treated would have increased survival with reduced toxicity then we probably would have tried keytruda in that it might not seem so much like playing Russian roulette.