They tied the hands and legs behind the back of Direct too then cut it off when an immune response began because of treatment response showing up like progression and yet patients without any other real options are alive today because of L and Direct. Your concerns are like those of one who thought the world was ending based on a falling acorn. The patients alive today after treatment with L or Direct might tell you and those who listen to you to watch out for any FOX that invites you to his den ; ). Best wishes.