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sunspotter

08/09/22 6:04 PM

#392183 RE: loanranger #392182

Just to explain further why the comparison was utterly invalid, not to say fraudulent, patients who were treated early from onset of symptoms would have received not just brilacidin but also standard of care including remdesivir and steroids.

Those who weren't treated early didn't receive any treatment until later in the course of the disease, and the pooled placebo group would have had many such patients.

As we already know remdesivir and steroids work better than no treatment, of course the early treatment group did better.

What this retrospective analysis doesn't tell us is whether or not brilacidin had any impact on that at all.

williamssc

08/09/22 7:16 PM

#392186 RE: loanranger #392182

Yeah right ss's point trumps the press release. Meanwhile NIH/NIAID is evaluating Brilacidin as a broad spectrum anti-virus.

frenchbroad

08/09/22 8:32 PM

#392190 RE: loanranger #392182

""Then again you LR failed to say these facts- "certain patient subgroups did show treatment benefits of Brilacidin for that primary endpoint. For example, patients treated early from onset of symptoms achieved sustained recovery more quickly (Brilacidin 5-dose group vs pooled placebo, p=0.03)."

I did. And I was about to apologize when I saw that SS had posted a very relevant explanation that I hadn't even considered. I'll put it into my own words but first I wanted to remind you that neither I nor any other participant here has the OBLIGATION to provide the same fulsome scientific details that the authors of that paper had. I only feel an obligation to the truth....no more, no less."

But you did not complain that the authors did not include "fulsome scientific details" for example that one dose of Brilacidin killed MRSA the same as 7 day infusion of Daptomycin. Did they have an OBLIGATION to say Brilacidin is tested with success against oral mucositis? They said nothing on this. Do you complain that the authors did not give "fulsome scientific details" about the fulsome testing of Brilacidin against infectious viruses paid by the USA government? They also said nothing on this. So they are bad scientists with poor science? Pfft.

I only feel an obligation to the truth....no more, no less.