Replies to post #462952 on NorthWest Biotherapeutics Inc (NWBO)

[Nick119]

Love it.

[hoffmann6383]

wow. any link to that screenshot? thanks for sharing

[slamminsalmon]

A stretch to associate that with DCVAX at this point, IMO

[branster]

Alpha, that tweet is from 2016 material.

https://ascopubs.org/doi/full/10.1200/EDBK_159084

[Nick119]

Unfortunately it's from 2016: https://ascopubs.org/toc/edbk//36

[pgsd]

The following replies to the tweet suggest it refers to a 2016 article.

Mark McCollum
@MarkMcCollum67

"2016"

@MinehanKern

https://ascopubs.org/toc/edbk//36

[GoodGuyBill]

https://ascopubs.org/doi/10.1200/EDBK_159084

KEY POINTS

--Immunotherapy has proven efficacy for other solid tumors and is now a focus for glioblastoma.

--An important component of glioblastoma-mediated immunosuppression stems from soluble factors such as TGF-ß.

--Checkpoint inhibition probably confers a nonspecific state of immune activation that is a promising approach to glioblastoma, given the success of checkpoint inhibitors in melanoma, lung cancer, and renal cancers.

--Current strategies for biomarkers have focused on protein expression, immune cell characterization, and mutational burden.

--Tumor-selective viruses and viral-based vectors have shown increasingly promising results as easy-to-use immunostimulants.