The logic is as follows R-IT results were stat sig within 21-23 months in a lower risk population. R-IT was roughly 70% secondary prevention. MITIGATE is 100% secondary prevention
R- IT median age of 62 MITIGATE ..I expect median age will be around 72 .
Bottom line ...MITIGATE is a higher risk population and a similar sized study as the subgroup covered in the recent publication .....