Gary, to your earlier post. I don’t think they were waiting on 248 deaths. What I was saying is that reaching 248 PFS events took substantially longer than anticipated (i.e, efficacy) but the powering to detect it was destroyed so LP marched on. Then we thought reaching 233 deaths was right around the corner, it wasn’t. It took a year and a half to reach, despite earlier data presented by Marnix, except that the first time they said 100 alive, they didn’t account for LTFU. This drug works really well and that is evident in the very long fat tail. As she continued to wait, it just got longer and fatter because the last 1/3 patients were nearly all treated, some at entry, others a few months delayed but before progression. There are no questions of efficacy. The outstanding question is how to establish a relatively uniform Synthetic control arm policy.
I just need us to get the answers soon. No one is getting any younger around here and I could use the pick me up right now.
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