TY. Very impressive that Avatar bested Lavender considering that the subjects were much older and their disease much further progressed. That's like subjects with moderate Alzheimers besting those w/MCI in drug trials. Impressive! AND the subjects didn't experience the prominent diarrhea and vomiting the Lavender girls did. Those side effects wreck havoc on their already disrupted GI tracts and may lead to malnutrition, weight loss, esophageal erosion, dental caries, insomnia, further mental stress, exhaustion, soiled nappies, filthy bums and vomit strewn about for caregivers to cleanup (gross). Those severe side effects take a toll over time on subjects and caregivers. Probably necessitating having to take a pill just to deal w/the side effects, or eventually needing to discontinue Trofinetide.