Sure. The only voice that I care about is the FDA’s. Let’s wait to hear what it has to say about the trial design.
My guess is that if the results are as good as advertised, A273 will be approved for Rett and it’ll be the last we hear from Adam F for a while. These type of clowns love to make a lot of noise from the tree tops, and then fly away silently when everyone stops listening.
a PR explaining the change in endpoints was at the request of the FDA
This narrative, "FDA made a request" is unproven. There were discussions with the FDA that resulted in change of the endpoints. That is how it was presented. "Request" is unproven.
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