Replies to post #439995 on NorthWest Biotherapeutics Inc (NWBO)

[hoffmann6383]

This is my point exactly. You are basing your opinion on a post from VuBru and completely disregarding a peer reviewed study with real world data. In other words, the basis of your opinion is flimsy at best.

I'd suggest you read the peer reviewed study directly on point with this subject, which can be found here:

https://jamanetwork.com/journals/jamaoncology/fullarticle/2678095

[The Danish Dude]

https://pubmed.ncbi.nlm.nih.gov/29710325/

Results: Of the 100 press releases in our sample, 70 (70%) reported positive results, but only 31 (31%) included the magnitude of study findings. Through the end of follow-up, 99 (99%) of press releases had an associated peer-reviewed publication, complete data posting to ClinicalTrials.gov, or both, with a median time to reporting of 300 days (95% CI, 263-348 days). Positive findings were reported more quickly than negative ones (median of 272; 95% CI, 211-318 days vs 407; 95% CI, 298-705 days; log-rank P < .001).

Conclusions and relevance: Even for the most pressing study findings, median publication delays approach 1 year. As publication delays hinder research progress and advancements in clinical care, policies that enable early preprint release or public posting of completed data analysis should be pursued.

So calculated from March 16 + 300 days is way too late still

You forgot the side effect of Covid-19. 321 days is still not extraordinary.

[VuBru]

Nope - Did not sell. I think they did not submit a manuscript until MUCH later than we had hoped, whether that is due to reanalysis using new GBM definition, some problem with data that required going back to individual sites (and covid impacts), wanting to wait until FDA formalized guidance on external controls, or whatever. If they submitted along the optimal publication timeline I had suggested, they would have had this published somewhere by now even under a worst case scenario (e.g., sending to 3 different journals). I still think the data will look good whenever they do come out, at least compared to external controls.

I loved the post recently about the guy's wife who saw a psychic saying TLD in March - that is as good a source of information as any!