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tredenwater2

01/14/22 10:31 AM

#344736 RE: hnbadger1 #344708

Maybe the FDA needed to see more proof of A2-73s MOA?



OLE analysation!
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Jonjones325

01/14/22 10:37 AM

#344744 RE: hnbadger1 #344708

Agreed. Especially since these PDD results have never been seen before.

Maybe Avatar together with the PDD OLE will be strong enough to make something happen.

What? Who knows but it seems that future trials are being held up and looking for definitive direction.

Data dependent
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frrol

01/14/22 12:03 PM

#344775 RE: hnbadger1 #344708

PDD is such a different indication that it's highly unlikely. The Rett TLR may be holding up the rest of the neurodevelopmental rare disease program.
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TempePhil

01/15/22 2:22 PM

#344981 RE: hnbadger1 #344708

hnbadger, holdup of pipeline updates explained
in this post.
I wrote this two months ago, and think it is still correct. The trials "undisclosed" and Angelman and FragileX are related to, and dependent upon the Rett Avatar results.

I suspect when the Avatar TLD PR comes out, there will be numerous communications soon afterwards, updating the other trial statuses.