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LakeshoreLeo1953

12/24/21 9:13 AM

#341094 RE: Gator328 #341092

vs. those who sold and reset the clock



While the vastly more common tax treatment, careful of generalizations
as to trading vehicle assumptions. MY Roth was WELL WORTH the conversion.
600K upon retirement in '07 and will let those interested in such things
to extrapolate likely valuation in '22 given dart board Market for much of that time.

end2war

12/25/21 12:45 AM

#341149 RE: Gator328 #341092

in fact, I’d argue we are in the thickest part of the woods because to date we really haven’t received the thorough scrutiny of an FDA review.



Does anybody think the delay in discussing the Avatar results could be that AVXL is waiting to report the topline data AND the results of a PH2 meeting with the FDA?

Fireman02360

01/04/22 6:21 PM

#342573 RE: Gator328 #341092

20x without any fundamental changes other than perception of the odds of success



Of course, isnt this what investing in pre-rev biotech is all about? For me, and many others, its not about investing AFTER successful commercialization of 2-73, by then, most of the real, high-dollar profits will have already have been made. I want in at ground-floor. I placed my bets. Usually, where there is smoke, there is fire (no pun) and IMO this drug would have failed long ago. I could be wrong, but dont think so. I would say drug failure at this point is very low. Most of these CNS indications only require a slight benefit over SOC. Some (Rett) have ZERO treatments so even small changes in behavior and over-all well being can be a gold-mine. Bu only for those willing to take the risk.

he stock has been a money maker to those who have traded in and out, like yourself.



I have traded this stock yes, but always have maintained a HUGE core of shares and still holding some form the low-$1 range. I am in this for the long-haul and IMO this is just getting started. It may take another year but $50 may be a distant memory. Hell, $150 maybe as well if 2H/2022 ALZ results are what we believe.

Happy New Year Gator.

-Fireman