Replies to post #428471 on NorthWest Biotherapeutics Inc (NWBO)

[dennisdave]

I dont understand what you are getting at you mean to hint/say that NWBO is referring to Advent specifically as their GMP for the UK or do you mean to say that it is THEIR entity as in subsidiary (which would be a falsehooid its Toucan’s)?

[IkeEsq]

Advent Bioservices, NWBio’s UK entity contract manufacturer

I would read that as Advent Bioservices being a 'UK entity' that NWBO has contracted with to manufacture its products. While it may read differently in British English, that is how I would read it as an American lawyer. It may be significant that Advent is a UK entity in order to be allowed to do certain things.

[longfellow95]

Well yes, in terms of literal meaning; Advent is a UK firm.
And yes they are NWBO's contractor.

Between the lines, you could intuit a bit of further implicit meaning; that Advent first and foremost serves NWBO. Any work they take on must be consented to by NWBO, and NWBO will always have first call on facility resources and capacity allocation.
And the UK location suggests to me that NWBO's likely focus for ongoing operations is going to be the UK first, Europe second, and the US and Canada after that.
Which is fine by me, as it appears to be the rational way to go.
In the short-term, I imagine patients will be from or come to the UK, thus limiting any long-distance supply logistics, with their associated costs and regulatory complexities.
Cognate is no more; I really don't know if they are still paying to retain any reserved capacity at Memphis. If they are, I would be wondering what for....
They can't really focus on all fronts at the same time with their limited resourcing, and their apparent current primary focus on the UK does seem a logical one.
Even if one is not a total fan of every single aspect of LP's stewardship, you really have to hand it to her; the way she has got NWBO to their current position of now being poised to move forward (hopefully) to active commercial operation.