In this price range, we are already in "trial failure" range despite that will never come.
I would put the trial failure market cap at about $200M at most, and that is a PPS of .15 or so on a fully diluted basis.
My basis of a post failure market cap is what an operational CDMO with a 4.4k sq-ft facility worth. Then I cut it in half because nobody knows how much will be Advent' when the dust clears.
And I think I am being generous.
Buy as many as you can afford, I even encourage those who have not had a position yet because of lack of funds, take a small loan and start buying.
Taking out loans to buy shares in a dev stage bio is outright gambling.