Replies to post #384733 on Innovation Pharmaceuticals Inc (IPIX)

[Hugon]

Inhaler should take 2 -3 years to test and complete through a $5m phase 1. Are you paying for that development? Don’t ya think Covid will be solved by then?!

[williamssc]

The antiviral virucidal blocking properties of B would be a huge market if also implemented against yearly cold and viruses. Would like to see more on this effort.

"Initial feasibility work to formulate Brilacidin for potential prophylactic use via inhaled delivery, to leverage Brilacidin’s unique virucidal and blocking antiviral properties, also is underway."

[sunspotter]

"it is more than reasonable to study Brilacidin as an inhaled therapeutic."

DeGrado's comment was about its use as a prophylactic:

"developing Brilacidin for potential prophylactic use by targeting the nasal passageway and lungs may be a particularly appealing clinical pathway"

That's never going to happen.

Besides, inhaled insulin was a massive commercial failure.

And an inhaler that causes hypertension and (allegedly mild) peripheral neuropathy is likely to have an even tougher time.

Even if it worked, and that has to be in question now.

The effect on viral load from the brilacidin study will tell us - if the information is ever released - if, as I suspect, the in vitro effect doesn't translate into in vivo activity.